Synthesis, characterization, DFT/TDDFT calculation and superoxide dismutase activity of copper(II) complex with ligand derived from benzil and cysteine
نویسندگان
چکیده
The condensation product of benzil and amino acid cystein has been isolated and used to form mononuclear complex with Copper(II) (Cu(II)L). The ligand (L) has been characterised by – UV/visible, FT-IR, H and C NMR, ESI Mass spectroscopy etc. The Cu(II)L complex has been characterised by various spectroscopic techniques UV/visible, FT-IR, ESI Mass, EPR and Thermo Gravimetric Analysis. The structure of Cu(II)L has been optimised by DFT calculation. TDDFT calculation has been performed to predict UV/Visible spectrum of Cu(II)L which is identical to the experimental one. Cyclic voltammogram showed quasi reversible behaviour with redox potential value -0.680 V at Platinum working electrode with Ag-AgCl (1 M NaCl) as reference electrode. Cu(II)L showed superoxide dismutase activity with IC50 value 7.8x10 -6 M.
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